Introns in Cryptococcus
نویسندگان
چکیده
منابع مشابه
Introns in Cryptococcus
In Cryptococcus neoformans, nearly all genes are interrupted by small introns. In recent years, genome annotation and genetic analysis have illuminated the major roles these introns play in the biology of this pathogenic yeast. Introns are necessary for gene expression and alternative splicing can regulate gene expression in response to environmental cues. In addition, recent studies have revea...
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Cryptococcosis, one of the most important systemic mycosis in the world, is caused by different genotypes of Cryptococcus neoformans and Cryptococcus gattii, which differ in their ecology, epidemiology, and antifungal susceptibility. Therefore, the search for new molecular markers for genotyping, pathogenicity and drug susceptibility is necessary. Group I introns fulfill the requisites for such...
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Most Cryptococccus neoformans genes are interrupted by introns, and alternative splicing occurs very often. In this study, we examined the influence of introns on C. neoformans gene expression. For most tested genes, elimination of introns greatly reduces mRNA accumulation. Strikingly, the number and the position of introns modulate the gene expression level in a cumulative manner. A screen for...
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type description (DTD). The DTD is the classification system that defines the different types of information pieces in any document. In each DTD the key XML 'tags', or descriptors, are described. Any one DTD can be used as the rule-set for any number of XML documents. This is the aspect of XML that is of most importance to scientists, because of its potential to improve dramatically the ability...
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The intron has been a big biological mystery since it was first discovered in several aspects. First, all of the completely sequenced eukaryotes harbor introns in the genomic structure, whereas no prokaryotes identified so far carry introns. Second, the amount of total introns varies in different species. Third, the length and number of introns vary in different genes, even within the same spec...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 2018
ISSN: 1678-8060,0074-0276
DOI: 10.1590/0074-02760170519